Liverpool sit top of the table after a 2-1 win over Leicester City, the first time that their defence has been breached.
bet365 are an industry best price of 11/4 (3.75) about Jurgen Klopp's side finishing the season top of the table in their latest Premier League odds.
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The Reds remain the nearest challengers to Manchester City, who got back to winning ways with a 2-1 victory over Newcastle United. Despite sitting two points off the early pace, bet365 have kept the reigning champions as 4/6 (1.67 ) favourites to ensure the top-flight trophy remains at the Etihad Stadium.
Maurizio Sarri has led his Chelsea team to four straight victories and the Blues are now 10/1 (11.0) to win a third title in five years.
The Londoners face Cardiff and West Ham in their next two league matches so it would be no surprise if they shortened up further in the betting ahead of hosting Liverpool at the end of the month in a mouth-watering clash.
Having been as big as 1000/1 (1001.0) with bet365 pre-season, Watford are the only other team with 12 points after a win over Tottenham. bet365 don't foresee the Hornets being realistic contenders, despite their impressive start but Javi Gracia's side have been cut to 250/1 (251.0) with the online firm.
After that 2-1 reverse at Vicarage Road, Spurs are available at 16/1 (17.0) from 10/1 (11.0) to win their first Premier League title.
Manchester United got a much-needed win over Burnley at Turf Moor but bet365 still make Jose Mourinho's side 40/1 (41.0) to turn around their disappointing start and end up as champions.
United visit Watford in their next league game and that trip looks likely to be another stern examination of their credentials which have been called into question after two defeats in the early stages of the new season.
Arsenal's unconvincing display in victory against Cardiff City sees the Gunners priced at 50/1 (51.0) in the outright market with Everton, Leicester City and Wolverhampton Wanderers all available at 500/1 (501.0) .
Check out the latest Premier League odds at bet365
