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Ecuador welcome Argentina to Quito on Tuesday in the final game of what has been a hugely successful CONMEBOL World Cup qualifying tournament for both sides.
Indeed, both nations have already secured their respective places at Qatar 2022, although there is still plenty of motivation heading into the final game.
The Albiceleste will be aiming to avoid defeat and remain unbeaten throughout the entire qualifying tournament, while the hosts will be hoping for the win which would confirm third place for them in the standing, a major achievement for the fourth-lowest world ranked CONMEBOL side.
Ecuador vs Argentina latest odds
Argentina have an excellent recent record against La Tri, winning five of their last six meetings, including a 3-1 success in their last trip to Quito for a World Cup qualifier in 2017.
Next matches
Another victory for Lionel Scaloni's side can be backed at 23/20 (2.15) with bet365 while the hosts are priced at 12/5 (3.40) and the draw at 9/4 (3.25).
Ecuador vs Argentina first goalscorer
Lionel Messi put in a superb performance in the side's 3-0 win over Venezuela at the weekend and the game in Quito is likely to be the 34-year-old's last World Cup qualifier as he seriously considers international retirement after Qatar 2022.
The PSG forward is priced at 7/2 (4.50) to net first, with Angel Di Maria at 9/1 (10.00) and Ecuador's top scorer Michael Estrada offered at 8/1 (9.00).
Ecuador vs Argentina preview
Five of Ecuador's seven wins in the tournament have come in front of their own fans, and a visit to the oppressive altitude of Quito remains one of the toughest trips in world football.
Argentina, however, will be confident of putting in another strong showing, with the two-time World Cup winners playing extremely well in recent months.
The Albiceleste have been rock-solid defensively, keeping clean sheets in eight of their last nine qualifiers, although they are up against the second top scorers at home in the competition, with Ecuador netting 18 times in their eight matches in front of their own fans.
Despite qualification having been secured by both teams already, Tuesday's game in Quito should be a competitive affair.
Ecuador vs Argentina tips & predictions
Both teams to score at 6/5 (2.20) could be an attractive option while the draw at 9/4 (3.25) could also be an interesting value selection.
Odds correct at the time of writing. 18+. begambleaware.org
Best Bet
Both teams to score at 6/5 (2.20) for a 1pt stake with bet365bet365